Cuomo, during an appearance before the Syracuse Post-Standard's editoral board Wednesday, stayed neutral when asked his thoughts on Weiner entering the race.
"He runs? He runs," the paper quotes him as saying in a transcript.
But asked how he would feel if Weiner (self-pictured at right) were to be elected, Cuomo was blunt.
"Shame on us," he replied.
Cuomo, a Democrat, has said he has no plans to get involved in the mayor's race.
He gave a less definitive answer hours before he spoke to the Syracuse paper when asked by reporters in Buffalo for his reaction to Weiner's mayoral bid.
“None,” Cuomo said.
"No reaction. Look, my face didn’t move. No reaction."